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The best serums are formulated with high concentrations of active ingredients, targeting specific skin concerns. Typically thinner in texture, serums penetrate deeply into the layers of the skin. Choosing the right serums can brighten your skin complexion, reduce the visible signs of aging and hydrate your skin.

If you have more than one skin concern, such as damaged skin, dark spots and fine lines and wrinkles, can you use multiple serums at the same time? 

You Can Absolutely Mix and Match Serums, the Key is the Order of Application

Most experts agree that 3 is the magic number of serums to layer at one time. 

  1. Start with cleansing your skin. Exfoliating regularly (anywhere from 1-2 a week to a few times a month) can help slough off dead skin cells so that your skin can absorb serums more efficiently. 
  2. To maximize absorption, apply products to skin that is slightly moist.   
  3. Start with the most active, water-based or most lightweight serum first, specially formulated to penetrate deeply into the skin. 
  4. Wait 2-3 minutes for each serum to completely absorb before applying the next one. 
  5. Layer with heavier weight, hydrating serums on top. 
  6. Follow with a moisturizing serum or, if you’re wondering when to apply a face oil, this can help seal in moisture and protect the skin barrier. 

Can You Layer Face Serums that are Great for Oily Skin and Still Reduce Signs of Aging? 

A good combination of serums for oily skin as well as combating aging is Hyaluronic Acid + Vitamin C Serum, Vitamin B5 Hydration Serum, and Matrixyl 3000 Serum

  • Hyaluronic Acid + Vitamin C serum boosts and maintains hydration while the lower concentration of Vitamin C (without Vitamin E or additional oils) is ideal for more sensitive or oily-prone skin. 
  • Vitamin B5 serum soothes inflammation and helps heal and repair skin. 
  • Matrixyl 3000 Serum contains peptides that improve overall skin elasticity, firmness and texture and is recommended for all skin types, especially those with sensitive skin.  

Mixing Serums to Brighten Your Complexion and Hydrate your Skin 

Antioxidants and peptides can help with the visible signs of aging.

  • To help combat dull skin and dark spots (hyperpigmentation) 20% Vitamin C + E Ferulic Acid Serum offers the most potent and bioavailable form of Vitamin C L-Ascorbic Acid. It helps even out and brighten skin tone while protecting against environmental stressors. Vitamin E and Ferulic Acid provide additional antioxidant protection and oil while stabilizing the Vitamin C. 
  • Or try CoEnzyme Q10 Serum to help energize skin cells to rebuild and collagen and elastin. This antioxidant also helps protect against sun damage while the 8% concentration of Matrixyl 3000 contains peptides to stimulate collagen synthesis.
  • Layer with Hyaluronic Acid 100% Pure, you can add it to your moisturizer to rehydrate and keep the skin healthy, glowing and plump.
  • Finish with a facial oil such as Squalane Oil 100% Pure to help keep your glow on all day, and serve as a primer before makeup.

Mix and Match

It’s okay to try different serum combinations to find the ones that work best for your skin type. You may also want to adjust your skincare routines by season, using a different combination of serums, such as Vitamin B5 serum for more oily skin in warmer summer months and 20% Vitamin C + E Ferulic Acid for dry, dull, uneven skin tone skin during colder winter months. 

Very sensitive skin may react adversely to serums because of their high concentration. A potent polypeptide serum, such as Matrixyl Synthe 6 Serum, for example, is best for non-sensitive skin types looking to restore firmness, elasticity and reduce fine lines and wrinkles.  

Choosing the Right Serum for You

With all the serum choices available, finding the one that is right for your skin and meets your needs can take time. A full skin cycle is approximately 28 days, so be patient when using new products as it usually takes a few skin cycles before you start to see results. Give your skin some time to adjust to these new ingredients. As long as you are consistent in your routine, you’re on your way to healthier, more rejuvenated skin!



DISCLAIMER: The information on our blogs has been compiled from published sources and the experience of the Timeless Skin Care team. The blogs are  not intended to diagnose or treat a medical condition or to address every skin type or  condition. While reasonable effort is made to publish reliable and up to date information, Timeless Skin Care cannot predict how a skin care regimen will affect every individual user. Timeless does not guarantee any specific outcomes or the accuracy of all information presented and accepts no liability in respect of any omission or error. If you are uncertain about possible sensitivity when using Timeless Skin Care products, please do a patch test before use. If you have any skin concerns, please talk to your physician or consult a dermatologist.