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Matrixyl® Synthe'6® Serum | Pouches
Science-backed ingredients graphic for Timeless S6 Serum highlighting Matrixyl® Synthe’6®, Hyaluronic Acid, and Aloe Barbadensis with firming and hydrating benefits.
Clinical Results After 14 Days graphic showing 100% improved skin firmness, 100% improved skin elasticity, and 84% visibly reduced wrinkles.
Smiling mature model with callouts: reduces fine lines and wrinkles, increases firmness and elasticity, and hydrates and restores skin.
5-star review card titled “Skin Never Looked Better” next to a Timeless S6 Serum sample packet on a pink background.
Graphic reading “Powerful anti-aging polypeptide serum for firmer, more youthful skin” targeting pronounced expression lines, fine lines, and wrinkles.
Close-up of a model holding a Timeless S6 Serum sample packet over one eye.
Matrixyl® Synthe'6® Serum | Pouches
Matrixyl® Synthe'6® Serum | Pouches
Science-backed ingredients graphic for Timeless S6 Serum highlighting Matrixyl® Synthe’6®, Hyaluronic Acid, and Aloe Barbadensis with firming and hydrating benefits.
Clinical Results After 14 Days graphic showing 100% improved skin firmness, 100% improved skin elasticity, and 84% visibly reduced wrinkles.
Smiling mature model with callouts: reduces fine lines and wrinkles, increases firmness and elasticity, and hydrates and restores skin.
5-star review card titled “Skin Never Looked Better” next to a Timeless S6 Serum sample packet on a pink background.
Graphic reading “Powerful anti-aging polypeptide serum for firmer, more youthful skin” targeting pronounced expression lines, fine lines, and wrinkles.
Close-up of a model holding a Timeless S6 Serum sample packet over one eye.
Matrixyl®️ Synthe'6®️ | Pouches
Matrixyl® Synthe'6® Serum | Pouches
Benefits
How it works
Directions
Ingredients
  • Restores firmness to the skin
  • Stimulates collagen & elastin production
  • Increases skin elasticity
  • Diminishes pronounced fine lines & wrinkles
  • Promotes optimal skin hydration levels

Matrixyl® Synthe'6® Serum | Pouches

Timeless Skin CarePowerful anti-aging peptide
5.0
Rated 5.0 out of 5 stars
16
$20.95

About Product

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN


The Restorer - Help turn back time on the visible signs of aging with Matrixyl® Synthe’6®. With six critical skin-building essentials, this powerful polypeptide targets pronounced wrinkles and expression lines by stimulating collagen production. Along with the ultra-hydrating properties of Hyaluronic Acid, it helps tired, damaged skin, and treats pronounced wrinkles and sun damaged skin. Lifts and plumps to reveal firmer, younger-looking skin. Beneficial for skin on the neck and décolleté.  Now, in new, single use packaging, perfect for travel and for on-the-go! Each box comes with a one month supply (28 pcs).

Recommended for: All skin types, especially dry and mature skin

Targets: Visible signs of aging, Wrinkles

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Benefits
How it works
Directions
Ingredients
  • Restores firmness to the skin
  • Stimulates collagen & elastin production
  • Increases skin elasticity
  • Diminishes pronounced fine lines & wrinkles
  • Promotes optimal skin hydration levels
APPLICATION: Apply and smooth contents of single use pouch onto freshly cleansed face and neck. Wait until the product has fully absorbed into the skin before the next step in your routine.

FREQUENCY: Use daily, PM use recommended for best results as skin cells are in a restorative mode while asleep.

Benefits
How it works
Directions
Ingredients

Clinical Trial Results

*Based on a clinical trial of 25 participants ages 20-58, after 14 days of use. Performed by a third party.

100%

had improved skin firmness

100%

found improved skin elasticity

84%

had visibly reduced wrinkles

FAQs

What is the shelf life of the Matrixyl® Synthe’6® Serum?
For best results, we recommend using your Matrixyl® Synthe’6® Serum within 24 months of receipt. For further guidance and customer consideration, the period after opening symbol is provided on the product box. Use upon receipt and refrigeration is suggested to assist with the shelf life of the product.
How long does the Matrixyl® Synthe’6® Serum product last with daily use?
With the suggested daily use amount of 2-3 drops, a 1oz bottle of Matrixyl® Synthe’6® Serum typically lasts about 1 month
Can I use the Matrixyl® Synthe’6® Serum under the eyes?
We do not recommend applying the Matrixyl® Synthe’6® Serum directly to the under-eye area. The skin around the eyes is very delicate, therefore, we recommend using products specifically formulated for eye area instead.
5.0
Rated 5.0 out of 5 stars
Based on 16 reviews
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16 reviews
  • Madonna D.
    Verified Buyer
    I recommend this product
    Age 60+
    Skin Type Dry
    Skin Concerns Dryness, Wrinkles & Fine Lines, Lifting & Firming
    Rated 5 out of 5 stars
    11/30/25
    Portable

    I’ve been using it for 8 years and as long as the package has been available, I’ve been a convert. I travel a lot and it just makes life so much more convenient.

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  • Lanie B.
    Verified Buyer
    I recommend this product
    Age 60+
    Skin Type Dry
    Skin Concerns Hyperpigmentation, Redness & Sensitivity, Dryness, Lifting & Firming
    Rated 5 out of 5 stars
    10/15/25
    Love This Serum *Packaging is Brilliant!

    As with all Timeless products, this one does not disappoint. I am 67 years young with Rosacea, so I have very sensitive skin. This Matrixyl'6 Serum in the pouches makes my face so soft and it makes my skin stronger. I rebuilt my skin barrier using the Vitamin C, Matrixyl,'6 the B-6 Serum and their Squalene oil. My skin looks terrific. These products kept my face looking bright during the 10 grueling months I was in chemo for breast cancer. Thank you, Timeless. The health of my skin was one less thing I had to worry about amidst the whole scary treatment process.

    I love the freshness in the packets and they make my travel needs effortless. I no longer carry all those pesky bottles adding weight and taking up the room in my cosmetic bags. I used the Vitamin C in the bottle back to back with the one in the packet and there was a huge difference in the freshness and strength of the one in the packets. I would like to see Timeless make a niacinamide serum in the future. Here's to Timeless Skincare in upcoming 2026.

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  • Shelly V.
    Verified Buyer
    I recommend this product
    Age 45-60
    Skin Type Dry
    Skin Concerns Wrinkles & Fine Lines, Dryness, Lifting & Firming
    Rated 5 out of 5 stars
    6/19/25
    Love this serum!

    Love this serum! Not only are the packets perfect for travel, but the moisturization it provides, in addition to the peptides, is wonderful! I won't go without this product, along with the CoQ10 serum and 20% A+C+FA.

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  • Jana K.
    Verified Buyer
    I recommend this product
    Age 45-60
    Skin Type Dry
    Skin Concerns Wrinkles & Fine Lines, Lifting & Firming, Dryness
    Rated 5 out of 5 stars
    5/6/25
    Nice feel on skin after application.

    Time will tell how it improves my skin. So far... after a week on consistent use... my skin feels softer.

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  • Munara D.
    Verified Buyer
    I recommend this product
    Age 45-60
    Skin Type Combination
    Skin Concerns Dryness, Wrinkles & Fine Lines, Lifting & Firming, Hyperpigmentation
    Rated 5 out of 5 stars
    2/17/25
    My go to serum!

    Matryxyl Cynthe 6, CoQ10, and Vit C serum are my first line of defense to keep my skin feeling, looking, and acting younger. Excellent products, service, and packaging. I noticed that pouches are more convenient for me than glass bottles because I travel often.

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