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  • Restores firmness to the skin
  • Stimulates collagen & elastin production
  • Increases skin elasticity
  • Diminishes pronounced fine lines & wrinkles
  • Promotes optimal skin hydration levels

Matrixyl® Synthe’6® Serum

Timeless Skin CarePowerful anti-aging peptide
4.9
Rated 4.9 out of 5 stars
1,920
$28.95
Size

About Product

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN


The Restorer - Help turn back time on the visible signs of aging with Matrixyl® Synthe’6®. With six critical skin-building essentials, this powerful polypeptide targets pronounced wrinkles and expression lines by stimulating collagen production. Along with the ultra-hydrating properties of Hyaluronic Acid, it helps tired, damaged skin, and treats pronounced wrinkles and sun damaged skin. Lifts and plumps to reveal firmer, younger-looking skin. Beneficial for skin on the neck and décolleté. 

Recommended for: All skin types, especially dry and mature skin

Targets: Visible signs of aging, Wrinkles


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    • Restores firmness to the skin
    • Stimulates collagen & elastin production
    • Increases skin elasticity
    • Diminishes pronounced fine lines & wrinkles
    • Promotes optimal skin hydration levels
    APPLICATION: Use 2-3 drops onto clean skin and smooth with your fingertips. Wait until the product has fully absorbed into the skin before the next step in your routine.

    FREQUENCY: Use daily, PM use recommended for best results as skin cells are in a restorative mode while asleep.

    Effective for 24 months from the date of manufacture.
    Benefits
    How it works
    Directions
    Ingredients

    Clinical Trial Results

    *Based on a 14 day study of 25 participants ages 20-58, after 14 days of use. Performed by a third party.

    100%

    had improved skin firmness

    84%

    had visibly reduced wrinkles

    100%

    had improved skin elasticity

    FAQs

    What is the shelf life of the Matrixyl® Synthe’6® Serum?
    For best results, we recommend using your Matrixyl® Synthe’6® Serum within 24 months of receipt. For further guidance and customer consideration, the period after opening symbol is provided on the product box. Use upon receipt and refrigeration is suggested to assist with the shelf life of the product.
    How long does the Matrixyl® Synthe’6® Serum product last with daily use?
    With the suggested daily use amount of 2-3 drops, a 1oz bottle of Matrixyl® Synthe’6® Serum typically lasts about 1 month
    Can I use the Matrixyl® Synthe’6® Serum under the eyes?
    We do not recommend applying the Matrixyl® Synthe’6® Serum directly to the under-eye area. The skin around the eyes is very delicate, therefore, we recommend using products specifically formulated for eye area instead.
    4.9
    Rated 4.9 out of 5 stars
    Based on 1,920 reviews
    Slide 1 selected
    1,920 reviews
    • Dry E. S.
      Verified Buyer
      I recommend this product
      Age 60+
      Rated 5 out of 5 stars
      5/20/26
      Great product, and doesn't bother my dry eyes!

      I was looking for as pure a matrixyl serum as I could find. Phenoxyethanol preservative was a big no-no for my dry eye disease (as well as some other ingredients). This is one of the rare matrixyl products (or skin care products period), without phenoxyethanol! And it is one of the best rated for effectiveness as well!! I cannot use retinol products (dry eye again) and this helps take the place for anti- wrinkle, aging, collagen concerns! So happy I did my research and found this brilliant product!! Yay, Timeless!!

    • Summer
      I recommend this product
      Rated 5 out of 5 stars
      5/19/26
      5 Stars

      Probably the serum i didnt know i needed. Love this so much

    • Kristi K.
      Verified Buyer
      I recommend this product
      Age 45-60
      Rated 5 out of 5 stars
      5/18/26
      Smaller pores already

      I’ve only been using Matrixyl Synthe’6 for about a week and cannot believe how much better my skin looks. At 52 I don’t have high expectations but was hoping for more even skin tone and maybe less noticeable wrinkles. My skin no longer has dry patches and my pores are smaller. At night I follow this with Timeless argan oil. Very pleased so far.

    • Anne C.
      Verified Buyer
      I recommend this product
      Age 60+
      Rated 5 out of 5 stars
      5/1/26
      Super Serum

      Works like a charm on my wrinkles!

    • Tracy S.
      Verified Buyer
      I recommend this product
      Age 45-60
      Rated 5 out of 5 stars
      3/31/26
      My skin is so much happier!

      My once dull, dry, and flaky skin is now plump, glowing, and hydrated. My face is so soft now!