Timeless Skin Care
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Timeless Matrixyl Synthe’6 Serum in a pink dropper bottle on a white background.
Timeless Matrixyl Synthe’6 Serum bottle on a white background.
Graphic showing Timeless Matrixyl Synthe’6 Serum with science-backed ingredients listed: Matrixyl Synthe’6, hyaluronic acid, and aloe barbadensis.
Timeless Matrixyl Synthe’6 Serum next to clinical results after 14 days showing improved firmness, elasticity, and reduced wrinkles.
Smiling model next to text listing skincare benefits: reduces fine lines, increases firmness and elasticity, and hydrates skin.
Five-star review graphic for Timeless Matrixyl Synthe’6 Serum next to a hand holding the pink serum bottle on a pink background.
Text graphic reading “Powerful anti-aging polypeptide serum for firmer, more youthful skin,” with translucent serum bubbles on a white background.
Graphic listing what Timeless is made with and made without, above three smiling models on a white background.
Close-up of a model applying face serum with a dropper near her eye.
Timeless Matrixyl Synthe’6 Serum in a pink dropper bottle on a white background.
Timeless Matrixyl Synthe’6 Serum bottle on a white background.
Graphic showing Timeless Matrixyl Synthe’6 Serum with science-backed ingredients listed: Matrixyl Synthe’6, hyaluronic acid, and aloe barbadensis.
Timeless Matrixyl Synthe’6 Serum next to clinical results after 14 days showing improved firmness, elasticity, and reduced wrinkles.
Smiling model next to text listing skincare benefits: reduces fine lines, increases firmness and elasticity, and hydrates skin.
Five-star review graphic for Timeless Matrixyl Synthe’6 Serum next to a hand holding the pink serum bottle on a pink background.
Text graphic reading “Powerful anti-aging polypeptide serum for firmer, more youthful skin,” with translucent serum bubbles on a white background.
Graphic listing what Timeless is made with and made without, above three smiling models on a white background.
Close-up of a model applying face serum with a dropper near her eye.
Timeless Matrixyl Synthe’6 Serum in a pink dropper bottle on a white background.
Timeless Matrixyl Synthe’6 Serum in a pink dropper bottle on a white background.
Benefits
How it works
Directions
Ingredients
  • Restores firmness to the skin
  • Stimulates collagen & elastin production
  • Increases skin elasticity
  • Diminishes pronounced fine lines & wrinkles
  • Promotes optimal skin hydration levels

Matrixyl® Synthe’6® Peptides Serum

Timeless Skin CarePowerful anti-aging peptide
4.9
Rated 4.9 out of 5 stars
1,907
$27.95
$16.77 w/code VITC40
Size
1 oz 4 oz

About Product

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN


The Restorer - Help turn back time on the visible signs of aging with Matrixyl® Synthe’6®. With six critical skin-building essentials, this powerful polypeptide targets pronounced wrinkles and expression lines by stimulating collagen production. Along with the ultra-hydrating properties of Hyaluronic Acid, it helps tired, damaged skin, and treats pronounced wrinkles and sun damaged skin. Lifts and plumps to reveal firmer, younger-looking skin. Beneficial for skin on the neck and décolleté. 

Recommended for: All skin types, especially dry and mature skin

Targets: Visible signs of aging, Wrinkles


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    Benefits
    How it works
    Directions
    Shelf Life
    Ingredients
    • Restores firmness to the skin
    • Stimulates collagen & elastin production
    • Increases skin elasticity
    • Diminishes pronounced fine lines & wrinkles
    • Promotes optimal skin hydration levels
    APPLICATION: Use 2-3 drops onto clean skin and smooth with your fingertips. Wait until the product has fully absorbed into the skin before the next step in your routine.

    FREQUENCY: Use daily, PM use recommended for best results as skin cells are in a restorative mode while asleep.

    Effective for 24 months from the date of manufacture.
    Benefits
    How it works
    Directions
    Ingredients

    Clinical Trial Results

    *Based on a 14 day study of 25 participants ages 20-58, after 14 days of use. Performed by a third party.

    100%

    had improved skin firmness

    84%

    had visibly reduced wrinkles

    100%

    had improved skin elasticity

    FAQs

    Can I use Matrixyl Synthe’6 Multi-Peptide Anti-Aging Serum with prescription tretinoin?
    Yes. Matrixyl Synthe’6 can be used in the same routine as prescription tretinoin. Apply Matrixyl Synthe’6 first, then follow with tretinoin and moisturizer.
    Can I use Matrixyl 3000 and Matrixyl Synthe’6 with a growth factor serum? If so, what order?
    Growth factors and peptides both act as “messenger” ingredients. For best results, we recommend alternating peptide serums rather than layering multiple peptide products in the same routine. Apply products from thinnest to thickest.
    Can Matrixyl Synthe’6 be used with the Coenzyme Q10 Serum?
    We don’t recommend using multiple peptide serums in the same routine. For best results, use one peptide serum per routine and alternate as needed.
    4.9
    Rated 4.9 out of 5 stars
    Based on 1,907 reviews
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    1,907 reviews
    • Karen M.
      Verified Buyer
      I recommend this product
      Age 60+
      Skin Type Dry
      Skin Concerns Wrinkles & Fine Lines, Dryness, Lifting & Firming
      Rated 5 out of 5 stars
      1/20/26
      Great

      This product makes my skin feel like silk.

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    • Dianna F.
      Verified Buyer
      I recommend this product
      Age 45-60
      Skin Type Combination
      Skin Concerns Wrinkles & Fine Lines, Lifting & Firming
      Rated 5 out of 5 stars
      12/12/25
      Must Have in Daily Routine

      This makes such a difference in my skin's hydration, smoothing out wrinkles, and overall glow!

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    • Julie
      I recommend this product
      Rated 5 out of 5 stars
      12/9/25
      5 Stars

      One if my staple serums!

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    • Sara
      I recommend this product
      Rated 5 out of 5 stars
      12/5/25
      5 Stars

      Makes my skin look like glass!

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    • Rosa S.
      Verified Buyer
      I recommend this product
      Age 60+
      Skin Type Combination
      Skin Concerns Lifting & Firming, Wrinkles & Fine Lines
      Rated 5 out of 5 stars
      11/29/25
      Been using a couple years.

      I like this serum. I’ve been using it for about two years and it has definitely helped not only keep wrinkles away but else’s smooth out some I already had. My friends say I look younger and ask me what I’m using. A few have started using this and the Vitamin C serum.

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