Graphic showing Timeless Coenzyme Q10 Serum with science-backed ingredients listed: ubiquinone (CoQ10), hyaluronic acid, and Matrixyl 3000.

Timeless Coenzyme Q10 Serum bottle beside text reading “Clinical Results After 3 Weeks,” showing 100% reported more moisturized skin, improved firmness and elasticity, and visibly reduced wrinkles, with a clinical trial disclaimer at the bottom.

Model holding Timeless Coenzyme Q10 Serum next to text listing benefits like boosting elasticity, reducing fine lines, and protecting from environmental stressors.

Five-star review graphic for Timeless Coenzyme Q10 Serum next to a hand holding the serum bottle on a pink background.

Text graphic reading “Anti-aging multi-tasker for plump, more youthful skin,” with serum droplets on a white background.

Graphic listing what Timeless is made with and made without, above three smiling models on a white background.

Coenzyme Q10 Serum Award Winning Best Seller by Timeless Skin Care

Benefits

How it works

Directions

Ingredients

Powerful antioxidant defense
Minimizes visible signs of aging
Helps restore skin's firmness & texture
Repairs damaged skin
Protects skin cells against damage from free radicals
Stimulates production of healthy skin cells

Coenzyme Q10 + Peptides Serum

Name: Coenzyme Q10 + Peptides Serum
Brand: Timeless Skin Care
SKU: Q10-1
Price: 27.95 USD
Availability: InStock
Rating: 4.9 (3169 reviews)

Timeless Skin CareThe anti-aging trifecta

4.9

Rated 4.9 out of 5 stars

3,169

$27.95

About Product

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN

The Defender - Our Coenzyme Q10 Serum is made with three wrinkle-fighting superstar ingredients, Ubiquinone, Matrixyl® 3000 and 100% Pure Hyaluronic Acid, and is the ultimate defense against the visible signs of aging. Coenzyme Q10 is a powerful, naturally-occurring antioxidant that energizes skin cells to rebuild collagen and elastin. Matrixyl® 3000, a safe alternative to Retinoids and Retinols, maximizes the synthesis of collagen in the skin, while Hyaluronic Acid increases and retains moisture for skin that looks and feels hydrated. This anti-aging trifecta works overtime to replenish and repair while smoothing fine lines & wrinkles.

Recommended for: All skin types, especially those with visible signs of aging. Not recommended for anyone with Vitiligo skin condition

Targets: Visible signs of aging, Wrinkles, Dullness, Hyperpigmentation, Discoloration

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Benefits

How it works

Directions

Shelf Life

Ingredients

Powerful antioxidant defense
Minimizes visible signs of aging
Helps restore skin's firmness & texture
Repairs damaged skin
Protects skin cells against damage from free radicals
Stimulates production of healthy skin cells

APPLICATION: Apply 2-3 drops onto fingers and spread the serum evenly over desired area. Wait until the product has fully absorbed into the skin before the next step in your routine.

FREQUENCY: Use Daily, AM or PM (recommended)

Effective for 24 months from the date of manufacture.

Benefits

How it works

Directions

Ingredients

Clinical Trial Results

*Based on a clinical trial of 20 participants ages 32-64, after 3 weeks of use. Performed by a third party.

100%

agree skin feels more moisturized and regenerated

100%

agree skin firmness and elasticity is improved

100%

agree wrinkles are visibly reduced

FAQs

Should I refrigerate the Timeless Coenzyme Q10 Serum?

The Coenzyme Q10 Serum is a stable formula and does not need to be refrigerated. However, storing it in the refrigerator is perfectly fine and will not harm the product.

Can I use the Timeless Coenzyme Q10 Serum with prescription tretinoin? Will they cancel each other out?

Yes. The Coenzyme Q10 Serum can be used in the same routine as prescription tretinoin, and the ingredients do not cancel each other out. The main product we recommend avoiding in the same routine as tretinoin is our Vitamin C + E Ferulic Acid Serum.

What is the shelf life of the Timeless Coenzyme Q10 Serum?

The Timeless Coenzyme Q10 Serum has a 24-month shelf life from the manufacturing date. Shelf-life details are also listed on each product page.

Can I use the Timeless Coenzyme Q10 Serum while pregnant or nursing?

Our products are generally considered safe for pregnant or nursing customers. However, we always recommend reviewing the ingredient list and consulting your healthcare provider before starting any new skincare product during pregnancy or breastfeeding.

If I use Coenzyme Q10 Serum and the 20% Vitamin C serum together in the morning, which goes first?

Apply serums from thinnest to thickest. Use the 20% Vitamin C + E Ferulic Acid Serum first, then follow with the Coenzyme Q10 Serum.

What’s the difference between the Coenzyme Q10 Serum and the Matrixyl 3000 Serum?

While both formulas contain Matrixyl 3000 and Hyaluronic Acid, they target different concerns. Matrixyl 3000 Serum focuses on supporting the look of firmness, elasticity, and fine lines using peptides. Coenzyme Q10 Serum provides antioxidant support and helps improve the look of uneven tone and discoloration with Ubiquinone (CoQ10). You can use both in your routine, either together or at different times of day.

Does the Timeless Coenzyme Q10 Serum contain any oil-based ingredients, or is it water-based?

The Coenzyme Q10 Serum is water-based and does not contain oil-based ingredients. A full ingredient list is available on the product page.

Is the Hyaluronic Acid in the Coenzyme Q10 Serum low or high molecular weight?

The Hyaluronic Acid in the Coenzyme Q10 Serum is medium molecular weight.

Can I apply the Coenzyme Q10 Serum under my eyes?

We do not recommend applying the Coenzyme Q10 Serum directly under the eyes. The under-eye area is delicate and best suited for products formulated specifically for that area.

What ingredients should I avoid using with the Coenzyme Q10 Serum?

For best results, we recommend avoiding using Coenzyme Q10 Serum in the same routine as chemical exfoliants, other peptide-focused serums, or retinoid derivatives, especially if you have sensitive skin. It can be used alongside Vitamin C and niacinamide, depending on your skin’s tolerance.

What’s the difference between the Coenzyme Q10 Serum and the Matrixyl serums?

The Coenzyme Q10 Serum combines antioxidant support (Ubiquinone/CoQ10) with peptides, while the Matrixyl serums are peptide-focused formulas. You can use both, or choose the one that best fits your skincare goals.

Is the Coenzyme Q10 Serum supposed to be yellow?

Yes. The natural color of Ubiquinone (CoQ10) is a yellow hue, and this is normal.

If I already use Vitamin C, do I need Coenzyme Q10 too?

Vitamin C and Coenzyme Q10 can complement each other. If you’re targeting dullness or uneven tone, layering CoQ10 with Vitamin C can provide added antioxidant support.

Should I apply CoQ10 before or after tretinoin (Retin-A)?

Apply Coenzyme Q10 Serum first, then follow with your tretinoin and the rest of your routine.

Can I use the Coenzyme Q10 Serum with Matrixyl serums?

For best long-term results, we recommend not using Coenzyme Q10 Serum and Matrixyl Synthe’6 in the same routine, since both are peptide-based formulas. Use them at different times of day instead.

What percentage of active ingredients are in the Coenzyme Q10 Serum?

This serum contains approximately 2% Ubiquinone (CoQ10), 8% Matrixyl 3000, and 1% Hyaluronic Acid.

How do I use the Timeless Coenzyme Q10 Serum in my routine?

Apply 2–3 drops to clean face and neck morning or night. Layer after lighter serums and before moisturizer. If used in the morning, finish with SPF.

Is the Coenzyme Q10 Serum suitable for sensitive skin?

It is formulated for most skin types, including sensitive skin. Patch test first and discontinue use if irritation occurs. It is not recommended for vitiligo.

4.9

Rated 4.9 out of 5 stars

Based on 3,169 reviews

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3,169 reviews

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Noreen E.
Verified Buyer
I recommend this product
Age 45-60
Skin Type Normal
Skin Concerns Redness & Sensitivity, Dryness
Rated 5 out of 5 stars
1/28/26
Q10 serum
Wonderful serum at a wonderful price! I have only used it for one week but my skin seems to really like it.. No redness or irritation which is a great thing! I will review this product again in another month. Thank you!
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Was this helpful?
Nikki S.
Verified Buyer
I recommend this product
Age 30-44
Skin Type Combination
Skin Concerns Wrinkles & Fine Lines, Dryness, Lifting & Firming
Rated 5 out of 5 stars
1/25/26
Love
I combine this and peptide serum with retinol at night. In the morning I use their vitamin c serum with this on top. My skin is so glowy and happy. Thank you!
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ava
Verified Buyer
I recommend this product
Age 18-29
Skin Type Oily
Skin Concerns Dryness, Acne
Rated 5 out of 5 stars
1/10/26
great
didnt expect to notice a difference when I stopped using this product. it genuinely makes my skintone so even and I repurchase the 4oz size.
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Karen
I recommend this product
Rated 5 out of 5 stars
12/15/25
5 Stars
This is my favorite serum from timeless. I will never go without it.
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Dianna F.
Verified Buyer
I recommend this product
Age 45-60
Skin Type Combination
Skin Concerns Wrinkles & Fine Lines, Lifting & Firming
Rated 5 out of 5 stars
12/12/25
Excellent
I use this daily and see wonderful results with smoothing out wrinkles, hydration, and glow.
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Coenzyme Q10 + Peptides Serum

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN

Clinical Trial Results

100%

100%

100%

FAQs

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Coenzyme Q10 + Peptides Serum

PARABEN FREE | SULFATE FREE | NO FRAGRANCE | DYE FREE | CRUELTY FREE | VEGAN

Clinical Trial Results

100%

100%

100%

FAQs

What are you looking for?