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Matrixyl®️ Synthe’6™️ Serum



Help turn back time on the visible signs of aging with Matrixyl®️ synthe’6™️. With six critical skin-building essentials, this powerful polypeptide targets pronounced wrinkles and expression lines. Along with the ultra-hydrating properties of Hyaluronic Acid, it helps tired, damaged skin. Lifts and plumps to reveal firmer, younger-looking skin. Beneficial for skin on the neck and décolléte. 

Recommended For:

  • Normal, Dry, and Mature skin   
  • Preventing visible signs of aging


    • Helps restore firmness to the skin
    • Improves skin elasticity
    • Repairs damaged skin
    • Promotes optimal skin hydration levels 

    How It Works

    Our Matrixyl S6 Serum contains a 2% concentration of Matrixyl®️ synthe’6™️, a powerful polypeptide that stimulates six major constituents of the skin matrix and dermal-epidermal junction (collagen I, II, IV, fibronectin, hyaluronic acid, and lamin 5). Combined with Hyaluronic Acid for powerful hydration, this serum helps reverse the signs of aging and smooths out deep wrinkles and fine lines.

    Guaranteed fresh and effective for 24 months from the date of purchase.


    Apply 2-3 drops to fingertips and smooth onto cleansed skin morning or night.


    Water, Matrixyl®️ synthe’6™️, Aloe, Glycerin, Hyaluronic Acid, Benzylalcohol, Dehydroacetic Acid.

    Timeless Promise

    • Paraben Free
    • Fragrance and Dye Free
    • Cruelty Free
    • More actives, less chemicals
    • Made in the USA

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    Customer Reviews

    Based on 1267 reviews
    Excellent Product

    Started using Matrixyl Synthe’ 6 a little over a month ago in conjunction with other Timeless products. My 61 year old skin, while not showing many signs of aging those that were creeping up are beginning to disappear. Very happy with all of the Timeless products that I use.

    So happy

    This serum makes my skin so soft

    Great product !

    52 years old and added Timeless to my skin care routine 4 weeks ago. I have age spots on cheeks from sun damage wrinkles around mouth and forehead. Mateyxol I started using this at night before retinol. During the day I use timeless vitamin C and then Great product. Not greasy smooth. Lovely feeling and my spots are lightening up. I use vitamin c and coenzyme Q10 during day and this at night

    Love Love Love this stuff!

    MATRIXYL®️ SYNTHE’6™️ SERUM works wonders on my skin! Leaves it feeling smooth and soft - well hydrated without being sticky or heavy... I use this daily and will not go without it!


    I am very happy with this product, I will by it again for sure

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